20:00-22:00 | Late Session |
20:00-20:15 | Welcome and Orientation Hülya Karataş, Müge Yemişçi Özkan |
20:15-22:00 | Introduction to Spreading Depolarizations: Consensus and Controversies with Audience Participation Jed Hartings , Cenk Ayata |
08:30-09:30 | Keynote Moderator: Muge Yemisci |
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Re-Evaluation of the Role of CSD in Migraine Headache Hayrunnisa Bolay |
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09:30-09:40 | Coffee Break | ||
09:40-12:05 | Oral Presentations Chair: David Chung, Lydia Hawley |
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Initial Results of The Indict Feasibility Trial of Spreading Depolarization Monitoring to Guide Management of Severe Traumatic Brain Injury Jed Hartings |
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Continuous Monitoring of Cerebrovascular Autoregulation Using Functional Ultrasound İmaging in The Piglet Brain Alan Urban |
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Spatial Dynamics of Human Spreading Depolarizations: Preliminary Results Applying a Newly Developed Two-Dimensional Strip Liangchen Guo |
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Cortical Spreading Depolarization During Surgical Management of Cerebral Arteriovenous Malformations and Arteriovenous Fistulas Patrick Dömer |
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10:45-11:00 | Coffee Break | ||
Spreading Depolarization Continuum in The Aged Non-Human Primate After Focal Ischemic Stroke Sergei Kirov |
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High-Frequency Oscillations During Cortical Spreading Depolarization Azat Nasretdinov |
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Noninvasive Optical Detection of Spreading Depolarization in Rat Elyssa Alber |
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The Introduction of a Novel Visualization Method of Cerebral Blood Flow Changes in Mice With an Rgb Camera: The Effects of Bosentan on Spreading Depolarizations Induced by Experimental Air-Emboli Model Via External Carotid Artery Cannulation Ergin Dileköz |
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12:05-13:00 | Lunch Break | ||
13:00-14:35 | Oral Presentations Chair: Jens Dreier, Melike Sever Bahçekapılı |
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Mems-Based Su-8 Neural Probes for Enhanced Neuromonitoring Hasan Uluşan |
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Noninvasive, Automated Detection of Spreading Depolarizations Using Scalp Electroencephalography:
A Multicenter Validation in Patients With and Without Skull Defect Alireza Chamanzar |
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Standardising Direct Cortical Response Monitoring of Spreading Depolarisations:
A Matlab-Based Approach For Automating Optimal Stimulation Channel Selection Khevna Vasani |
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Noninvasive Vs. Invasive Detection of Cortical Spreading Depolarization Via Dc-Shift Comparison Stephen Jones |
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Step Response of Metallic Electrodes Kevan Hashemi |
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Monitoring High-Resolution Electrophysiological Activity of Brain Slices With A Multi-Functional High-Density Microelectrode Array Hasan Ulusan |
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14:35-16:30 | Posters with Coffee+Snacks | ||
Detection of Spreading Depolarization-Associated Blood-Brain Barrier Disruption Using Dynamic Contrast-Enhanced MRI Magnus Kreiberg |
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Impairment Of Na+-K+-Atpase in The Human Cortex Under Halogenated Ether Anesthetics is Associated with Disrupted Ion Homeostasis Mathilde Maechler |
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Electrophysiological Characterization of The Pericyte-Endothelial Cell Syncytium in Human Brain Slices From Patients with Pharmacoresistant Mesial Temporal Lobe Epilepsy Mirja grote Lambers |
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Case Report: A Patient With Hemiplegic Migraine And Unilateral Transient Cerebral Hyperperfusion Yasemin Gürsoy Özdemir |
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Protocol Overview: Inhibiting The Nmdar/Trpm4 Interaction as a Neuroprotective Strategy in a Gyrencephalic Brain Model of Ischemic Stroke Through Modulation of Spreading Depolarization Juan Manuel Lopez Navarro |
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A Mems-Based Thin Film Microelectrode Array For Monitoring of Traumatic Brain Injury Hasan Uluşan |
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Alzheimer-Stroke Continuum: The Role Of Spreading Depolarization Anna Törteli |
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Cognitive Impairment and Platelet Dynamics in Mild Traumatic Brain Injury: Insights from a North Indian Cohort Arulselvi Subramaniam |
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16:30-17:30 | Keynote Moderator: Cenk Ayata |
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Capillaries as Multi-Modal Sensors of Brain Activity Mark T. Nelson |
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20:00-21:00 | Late Night Roundtable | ||
SD and Migraine KC Brennan, Müge Yemişçi Özkan, Elif Akaydın |
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Is SD Good or Bad? Cenk Ayata, Kadir Oğuzhan Soylu |
08:30-10:05 | Oral Presentations Chair : Bill Shuttleworth, Else Tolner |
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The Impact of Cortical Spreading Depolarization on The Autonomous Nervous System in Critically Brain Injured Patients Gwendan Percevault |
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Impact of Sd İnitiation Site on Outcome of Transient Focal Ischemia Michael Bennett |
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Repetitive Cortical Spreading Depolarizations Exacerbate Tissue Damage and Neurological Deficits Following Traumatic Brain Injury Faith Best |
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Every Cloud Has a Silver Lining: Spreading Depolarization Induction of Neuroprotective Pathways Through Gene Expression Changes. Michela DellOrco |
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Correlation of BDNF Levels with Concussion Symptoms and Neurobehavior Deficits Associated with a Mild Traumatic Brain Injury Venencia Albert |
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Migrainous Infarction: Myth or Reality? A Systematic Review Emilie Schou |
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10:05-10:15 | Coffee Break | ||
10:15-12:00 | Oral Presentations Chair: KC Brennan, Annika Köhne |
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A Novel Model of In Vitro Cortical Spreading Depolarization Yasemin Gürsoy Özdemir |
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Olfactory Bulb Induction of Cortical Spreading Depolarization Muhammed Miran Oncel |
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Effect of Long-Term Optogenetic Stimulation on Electrophysiological Spreading Depolarization Parameters in Mice Annika Köhne |
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Loss of Arousal Following Induction of Cortical Spreading Depolarisation in Awake Mice Kağan Ağan |
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Spontaneous Spreading Depolarizations in Atp1a2 And Atp1a3 Mutant Mice Else Tolner |
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Acute Levcromakalim Injection Induces Migraine-Like Phenotype Without Cortical Spreading Depolarization in Male Wistar Rats
Elif AKAYDIN |
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Palytoxin Evokes Reversible Spreading Depolarization in The Locust CNS
R. David Andrew |
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12:00-13:00 | Lunch Break | ||
TBA | The Antalya Museum (Antalya Archeological Museum) and Antalya Tour | ||
20:00-21:00 | Late Night Roundtables Clinical SD recordings Moderators: Martin Fabricius, Beyza Türken |
08:30-09:30 | Keynote Moderator: Hulya Karatas |
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Spreading Depolarization in the Waking Brain: Insights from Animal Models Lyudmila Vinogradova |
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09:30-09:40 | Coffee Break | ||
09:40-11:50 | Oral Presentations Chair: Yasemin Gürsoy Özdemir, Johannes Woitzik |
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The Slope of The Spreading Depolarization Related Blood Flow Transients is a Potential Biomarker for Risk Stratification in Experimental Ischemic Stroke Lückl Janos |
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Prophylactic Treatment of Migraine With (100%) Aura: Evaluating The Efficacy of Lamotrigine in Preclinical and Clinical Settings Buket Nebiye Demir |
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Impact of Nimodipine on Hemodynamic Fluctuations and Connectivity Dynamics Following Cortical Spreading Depolarizations in a Gyrencephalic Swine Model Diego Alberto Sandoval Lopez |
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Inhibition of Nitric Oxide Synthase Transforms Carotid Occlusion-Mediated Benign Oligemia into Large Cerebral İnfarction Dong-Eog Kim |
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10:30-10:45 | Coffee Break | ||
Hyperosmotic Treatment for Neuroprotection: In Vitro Effects of Mannitol Rita Frank |
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Effect of Sın-1 on The Sd-Initiated Nup and The No-Reflow Phenomenon During Forebrain Ischemia and Reperfusion in Rats Lemale Coline |
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Investigating the Effects of Nanoencapsulated Ketamine on Cerebral Blood Flow Responses Post Focal Cortical Ischemia Using Functional Ultrasound Imaging Lorena Figueiredo Fernandes |
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Blood-Brain Barrier Dysfunction in Abnormal Brain Predicts Epilepsy After Subarachnoid Hemorrhage Dreier Jens |
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11:50-12:55 | Lunch Break | ||
12:55-14:30 | Oral Presentations Chair: Eszther Farkas, Muhammed Miran Öncel |
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The Role of an Innate Immune System Pathway in Cortical Spreading Depolarization and Nociception Kadir Oguzhan Soylu |
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Does Spreading Depression Rewire Cortical Pain Networks? Bengisu Solgun |
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Cortical Spreading Depolarization-Induced Nlrp3 Inflammasome Activation Via P2x7 Receptor Activity in Trigeminal Ganglia Beyza Türken |
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How Spreading Depolarizations Shape Epileptic Activity Roustem Khazipov |
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Natural History of Seizures, Spreading Depolarizations And Seizure-Associated Spreading Depolarization in Mouse Models of Epilepsy. Rob Wykes |
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Seizure Propagation Triggers a Protective Contralesional Spreading Depolarization During Focal Hippocampal Stroke in Freely Behaving Female Mice Andrew Boyce |
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Characterization of Spreading Depolarization And Epileptiform Activity Following İnduction of Focal Cerebral Ischemia in Awake Mice. Samuel Flaherty |
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14:30-16:30 | Posters with Coffee+Snacks | ||
The Effect of Noninvasive Cortical Spreading Depolarizations on a Test of Executive Function Lydia Hawley |
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Nimodipine Reduces Microglial Activation by Spreading Depolarization and in Response To Lipopolysaccharide, As Evidenced by Morphological Phenotype and RNA Sequencing István Pesti |
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Pre-Stroke or Post-Stroke Spreading Depolarization and Ischemia Do Not Affect Stroke Outcomes in a New Mouse Model of Focal Ischemic Stroke, Naim Kyusun Han |
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Effects of Metabolic Inhibition on Intracellular CA2+ And ATP in Human Cortical Brain Organoid Slice Cultures (CBOS) Laura Petersilie |
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Activation of TRPV4 Channels Promotes The Loss Of Cellular Atp in Mouse Neocortex Exposed to Chemical Ischemia Nils Pape |
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Combined Dasatinib and Quercetin Treatment After Carotid Artery Stenosis Limits Spreading Depolarization During Subsequent Acute Ischemic Stroke in Aging Rats Szilvia Kecskés |
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Pro-Epileptic Effects of Spreading Depolarizations Daria Vinokurova |
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Impact of Cortical Spreading Depolarization on Neural Precursor Dynamics and Neurogenesis in The Adult Dentate Gyrus Anja Urbach |
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16:30-17:30 | Keynote Moderator: Jed Hartings |
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Clinical Neuromonitoring in the Intensive Care Unit: Spreading Depolarizations in Real Time and in the Real World Brandon Foreman |
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20:00-21:00 | Late Night Roundtable | ||
The Potential of Pharmacological Interventions Targeting CSD Pathways Hülya Karataş, Istvan Pesti |
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Carreer Discussions for SD Researchers: Grantsmanship and Promotion Jed Hartings, Melike Sever Bahçekapılı |
09:00-09:30 | Recap iCSD 2024 Britta Lindquist |
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09:30-09:45 | Oral and Poster Presentation Awards | ||
09:45-10:00 | Concluding Remarks |